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Session: ePoster Monitor 5-Colon Cancer 4

eP329 - Robotic versus Laparoscopic Pelvic Lateral Lymph Node Dissection in Advanced Rectal Cancer: A Systemic Review and Meta-analysis

Sunday, June 2, 2024
10:15 AM – 10:20 AM ET, USA
Location: Baltimore Convention Center, Room 318-320

    ePoster Presenter(s)

  • YC

    Yi-Chang Chen

    Attending surgeon
    China medical university hospital
    Kaoshiung medical university
    台中市, Taichung, Taiwan (Republic of China)

    All of the relevant financial relationships listed below have been mitigated.
    This individual has no financial relationships with ineligible companies.

    • Senior Author(s)

  • WC

    William Tzu liang Chen, n/a

    Superintendent
    China Medical University Hsinchu Hospital
    北區, Taichung, Taiwan (Republic of China)

    Disclosure information not submitted.

Purpose/Background: Comparative studies of robotic versus laparoscopic pelvic lateral lymph node dissection (PLNND) were still not conclusive regarding to the short- and long-term outcome. This study undertakes a rigorous meta-analysis with the objective of comparing and contrasting robotic and laparoscopic PLLND in the setting of advanced rectal cancer. By conducting a comprehensive review of existing literature and data, this research aims to enhance the current understanding and stimulate a more informed discourse regarding the most effective surgical approach for PLNND.Methods/Interventions: We searched PubMed, Embase, Web of Science database for papers comparing robotic to laparoscopic PLNND. Comparable data was pooled for meta-analysis.Results/Outcomes: There were 5 studies included and 567 patients were analyzed ,that included 301 laparoscopic PLLND surgeries and 266 robotic PLLND surgeries.Total operation time was significantly longer in the robotic group (difference in means=67.11, 95% CI (30.80, 103.42), P < 0.001) but no significant different in LLND time. Regarding to surgical morbidity, overall complication rate was significantly higher in laparoscopic group(OR=1.589, 95% CI (1.009,2.503), p=0.046), especially with respect to urinary retention(OR=2.23, 95% CI (1.277, 3.894), p=0.005) but no significant different in anastomosis leakage, ileus, wound complication, obturator nerve palsy. In the pathology outcome, robotic group could harvest more number of lateral lymph node(differences in means=1.992, 95% CI (1.563, 2.421), p < 0.001) but the distal margin of robotic group was shorter than laparoscopic group(differences in means=-2.827, 95% CI (-5.138, -0.517), p=0.016).Conclusion/

Discussion: Robotic PLLND is safe and feasible in rectal cancer surgery. Comparing with laparoscopic PLLND, robotic PLLND could harvest more number of lateral lymph node and lower overall complication rate, especially in urinary retention. In the future, large prospective trial will help evaluate the potential benefits of robotic PLLND in advanced rectal cancer."PRISMA flow design

PRISMA flow design
Study charactristics

Study charactristics
Forest plot of overall complication overall complication.tifForest plot of overall
Forest plot of PLLN numberFig05-number of PLND.tifForest plot of PLLN number"